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dc.contributorCNPQen-US
dc.creatorSabioni, Rafael Estevan
dc.creatorLorenz, Evandro Kleber
dc.creatorPossebon Cyrino, José Eurico
dc.date2017-10-23
dc.date.accessioned2020-11-05T13:36:09Z
dc.date.available2020-11-05T13:36:09Z
dc.identifierhttp://lajar.ucv.cl/index.php/rlajar/article/view/vol45-issue4-fulltext-19
dc.identifier10.3856/vol45-issue4-fulltext-19
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/158965
dc.descriptionProlonged stress hampers immune function and lessens disease resistance of fish, causing economic losses. Attention is thus been centered in the study of fish immunology. The main ‘in vivo’ models used in immunological studies are: stimulation of immune response (by immunostimulant molecules); induction of inflammation; induction of immunosuppression by chronic stress; or administration of drugs. This trial aimed at evaluating existing protocols for immunosuppression by drugs in fish, adapted to slow release implants model, using hydrogenated vegetable fat (HVF), with the intention of set a controlled immunodeficiency state model for advanced studies. The implant model was not efficient in reducing the immune response in a controlled manner. Evidence of self, down-regulation in fish immune system was found in implanted fish, what should be further investigated using molecular tools.en-US
dc.formatapplication/pdf
dc.languageeng
dc.publisherPontificia Universidad Católica de Valparaísoen-US
dc.relationhttp://lajar.ucv.cl/index.php/rlajar/article/view/vol45-issue4-fulltext-19/854
dc.sourceLatin American Journal of Aquatic Research; Vol 45, No 4 (2017); 828-832en-US
dc.sourcePlataforma para envío de artículos - Latin American Journal of Aquatic Research; Vol 45, No 4 (2017); 828-832es-ES
dc.source0718-560X
dc.source0718-560X
dc.subjectPiaractus mesopotamicus; homeostasis; immunomodulation; inflammation; leukocytes; stress; lymphocytesen-US
dc.titlePreliminary assessment of slow release implant model for immunosuppression in juvenile pacu (Piaractus mesopotamicus)en-US
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typeen-US
dc.typees-ES


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