Some studies have characterized and evaluated the parasitic load of the Pacific sardine. However, there are few studies related to its physiology and parasites load. This study aimed to evaluate the blood parameters and the abundance of helminth parasites of sardines obtained from two samples from Todos Santos Bay during autumn 2013. The digenea Myosaccium ecaude parasite was the only species registered. Sardines had a prevalence of 28%, an average abundance of 25 and an intensity of 7 parasites. There were no statistically significant differences (P > 0.05) in most of the analyzed blood parameters (red blood cell count, hematocrit, leukocyte cellular differentiation, mean corpuscular volume, total protein, glucose, alanine aminotransferase, osmotic pressure, Na, K, and pH) of fish with and without parasites, except in white blood cell count and in Ca concentration that showed a marked decrease. The relationship between parasite abundance and blood parameters, based on the results of this study, it is not clear due to the low parasitic load.Globally, the exploitation of sardines is of great importance due to food industry demand. Several studies on the Pacific sardine Sardinops sagax caeruleus have focused on the identification of stock composition to examine the population structure. However, there are few studies related to its parasites load. Parasite presence is important to evaluate, because this species is used for human consumption. Thus, the aim of this study was to assess the health status of the sardine of the Baja California temperate stock by evaluating the blood parameters and the abundance of helminthes parasites. Sardines were captured in two locations Todos Santos Bay and Cedros Island. The digenea Myosaccium ecaude parasite was the most abundant species although other parasites such as the Nematodes Anisakis sp. and Contracecum sp. and an Isopod of the Family Cymothoidae were registered. Sardines infected principally by M. ecaude in Todos Santos Bay had a prevalence of 28%, an average abundance of 25 and an intensity of seven parasites, while at Cedros Island, the prevalence was 85.50% with an average abundance of eight and an intensity of nine parasites. Amongst healthy and infected fish, there were no statistically significant differences (P > 0.05) in most of the analyzed blood parameters, except in total leukocyte count and in Ca concentration that showed a marked decrease. Results of this study show that will need more research to advance understanding of the relationship between parasite abundance and blood parameters in order to establish health status in the Pacific sardine.