Show simple item record

The antiproliferative potential of fungi associated with coral and algae collected from a Veracruz Reef System, Gulf of Mexico

dc.contributorCDHG thanks CONACyT for the scholarship for Master´s in Sciences studies at INBIOTECA-UV (No. 603960)en-US
dc.contributorthematic networks between academic groups PRODEPen-US
dc.contributorJMP thanks the Spanish Government: project PGC2018-094503-B-C22 (MCIU/AEI/FEDER, UE).en-US
dc.creatorEspinoza, César
dc.creatorHerrera-García, Carlos D.
dc.creatorEspinosa-García, Victoria
dc.creatorCouttolenc, Alan
dc.creatorAndrade-Torres, Antonio
dc.creatorPadrón, José M.
dc.creatorTrigos, Angel
dc.date2021-10-31
dc.date.accessioned2022-03-08T10:35:25Z
dc.date.available2022-03-08T10:35:25Z
dc.identifierhttp://lajar.ucv.cl/index.php/rlajar/article/view/vol49-issue5-fulltext-2704
dc.identifier10.3856/vol49-issue5-fulltext-2704
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/179281
dc.descriptionCoral reefs are ecosystems with great biodiversity and architectural complexity. Among these, marine fungi constitute one of the least studied groups, despite being potentially an inexhaustible source of bioactive metabolites. For this reason, in this research, we evaluate the antiproliferative activity of 52 fungal strains associated with marine organisms such as algae and coral collected from four islands located in the National Park Sistema Arrecifal Veracruzano, Mexico. One hundred four chloroform:methanol extracts corresponding to the culture broth, and biomass produced from each fungal strain was obtained from these. Subsequently, they were evaluated against six human solid tumor cell lines (HBL-100, HeLa, SW1573, T-47D, WiDr, and A549). The outcome was that six extracts showed activity against at least one cancer cell line. The identity of these fungi corresponded to the genera Nigrospora, Pestalotiopsis, Cladosporium, and Ochroconis according to their morphological and molecular analysis. In this sense, the strain found to have the highest antiproliferative potential [GI50 (μg mL-1) 4.6, 2.5, 8.0, 5.6, 52.0, 4.0] grouped phylogenetically with a species of Nigrospora sp. The preceding confirms that ecosystems provide.en-US
dc.formatapplication/pdf
dc.languageeng
dc.publisherPontificia Universidad Católica de Valparaísoen-US
dc.relationhttp://lajar.ucv.cl/index.php/rlajar/article/view/vol49-issue5-fulltext-2704/1482
dc.rightsCopyright (c) 2021 Latin American Journal of Aquatic Researchen-US
dc.sourceLatin American Journal of Aquatic Research; Vol 49, No 5 (2021); 843-849en-US
dc.sourcePlataforma para envío de artículos - Latin American Journal of Aquatic Research; Vol 49, No 5 (2021); 843-849es-ES
dc.source0718-560X
dc.source0718-560X
dc.subjectNigrospora; Pestalotiopsis; Cladosporium; Ochroconis; antiproliferative effect; marine fungien-US
dc.titleThe antiproliferative potential of fungi associated with coral and algae collected from a Veracruz Reef System, Gulf of Mexicoen-US
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typeen-US
dc.typees-ES


This item appears in the following Collection(s)

Show simple item record