In vitro antiviral, antioxidant and in vivo antipyretic activity of three South Africa medicinal plants crude extracts
Actividad antiviral, antioxidante y antipirética in vivo de tres extractos crudos de plantas medicinales de Sudáfrica
| dc.creator | Osunsanmi, Foluso O | |
| dc.creator | Yotwana, Lungelo | |
| dc.creator | Mosa, Rebamang A. | |
| dc.creator | Liu, Ai-Lin | |
| dc.creator | Gao, Li | |
| dc.creator | Du, Guan-Hua | |
| dc.creator | Opoku, Andy R | |
| dc.date | 2022-04-18 | |
| dc.date.accessioned | 2022-04-28T15:04:50Z | |
| dc.date.available | 2022-04-28T15:04:50Z | |
| dc.identifier | https://blacpma.ms-editions.cl/index.php/blacpma/article/view/307 | |
| dc.identifier | 10.37360/blacpma.22.21.5.38 | |
| dc.identifier.uri | https://revistaschilenas.uchile.cl/handle/2250/181923 | |
| dc.description | This study investigated anti-viral, antioxidant activity and anti-pyretic of crude extract from Artemisia afra, Artemisia absinthium and Pittiosporum viridflorum leaves. The crude extracts were prepared by maceration using aqueous, methanol and dichloromethane respectively. Antiviral studies were evaluated with influenza virus using Fluorescence based - Neuraminidase inhibitors. Antioxidant activities determined with DPPH, Nitric oxide, hydroxyl and super oxide anion radicals’ Anti-pyretic activities were evaluated using rats with yeast induced pyrexia. Total phenol, flavonoids, and pro-anthocyanin contents of the plants samples were evaluated using standard protocols. The crude extracts exhibited neuraminidase inhibitory activity against the influenza virus at different thresholds. Artemisia absinthium aqueous extract showed the best activity against A/Sydney/5/97. Whereas Artemisia afra methanol crude extract displayed highest antioxidant potential against the tested antioxidant parameters. All the crude extracts significantly reversed yeast induced pyrexia in rats, similar to paracetamol. Thus, they could serve as natural remedy for respiratory diseases such as Influenza. | en-US |
| dc.description | Este estudio investigó la actividad antiviral, antioxidante y antipirética del extracto crudo de hojas de Artemisia afra, Artemisia absinthium y Pittiosporum viridflorum. Los extractos crudos se prepararon mediante maceración utilizando metanol acuoso y diclorometano respectivamente. Los estudios antivirales se evaluaron con el virus de la influenza utilizando inhibidores de neuraminidasa basados en fluorescencia. Actividades antioxidantes determinadas con DPPH, radicales aniónicos de óxido nítrico, hidroxilo y superóxido. Las actividades antipiréticas se evaluaron utilizando ratas con pirexia inducida por levaduras. El contenido total de fenol, flavonoides y proantocianina de las muestras de plantas se evaluó utilizando protocolos estándar. Los extractos crudos mostraron actividad inhibidora de neuraminidasa contra el virus de la influenza en diferentes umbrales. El extracto acuoso de Artemisia absinthium mostró la mejor actividad contra A/Sydney/5/97. Mientras que el extracto crudo de Artemisia afra metanol mostró el mayor potencial antioxidante contra los parámetros antioxidantes probados. Todos los extractos crudos revirtieron significativamente la pirexia inducida por levaduras en ratas, similar al paracetamol. Por tanto, podrían servir como remedio natural para enfermedades respiratorias como la Influenza. | es-ES |
| dc.format | application/pdf | |
| dc.language | spa | |
| dc.publisher | MS-Editions | es-ES |
| dc.relation | https://blacpma.ms-editions.cl/index.php/blacpma/article/view/307/315 | |
| dc.rights | https://creativecommons.org/licenses/by-nc-nd/4.0 | es-ES |
| dc.source | Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas; Vol. 21 No. 5: September 2022; 620-630 | en-US |
| dc.source | Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas; Vol. 21 Núm. 5: Septiembre 2022; 620-630 | es-ES |
| dc.source | 0717-7917 | |
| dc.subject | Antivírico | es-ES |
| dc.subject | Antioxidante | es-ES |
| dc.subject | Artemisia afra | es-ES |
| dc.subject | Artemisia absinthium | es-ES |
| dc.subject | Pittosporum viridiflorum | es-ES |
| dc.subject | Antiviral | en-US |
| dc.subject | Antioxidant | en-US |
| dc.subject | Artemisia afra | en-US |
| dc.subject | Artemisia absinthium | en-US |
| dc.subject | Pittosporum viridiflorum | en-US |
| dc.title | In vitro antiviral, antioxidant and in vivo antipyretic activity of three South Africa medicinal plants crude extracts | en-US |
| dc.title | Actividad antiviral, antioxidante y antipirética in vivo de tres extractos crudos de plantas medicinales de Sudáfrica | es-ES |
| dc.type | info:eu-repo/semantics/article | |
| dc.type | info:eu-repo/semantics/publishedVersion |