In 1952, the Chilean First Lady Rosa Markmann received as a donation from two international laboratories, a significant quantity of drugs to treat tuberculosis, being Ditubin (hydrazide of isonicotinic acid or isoniazid) a drug of recent manufacture and tests, a light of hope for Chilean patients, so much so that the patients requested it calling it a “miracle drug”. In this study it is argued that this consort carried out an efficient task based on the distribution of these drugs throughout the country, with such positive results that, together with the rest of the political and social activities that it promoted, it helped to institutionalize a new role of the President's wife. The work has been carried out mainly based on the consultation of the letters that the Chileans sent to that First Lady, present in the National Archive, Gabriel González Videla fund and in the personal archive of the González Markmann family. Methodologically, a qualitative and a quantitative analysis of the correspondence has been carried out.En 1952, la Primera Dama chilena Rosa Markmann recibió como donación de parte de dos laboratorios internacionales, una cantidad importante de medicamentos para tratar la tuberculosis, siendo el Ditubín (hidrazida del ácido isonicotínico o isoniacida) medicamento de fabricación y pruebas recientes, una luz de esperanza para los pacientes chilenos, tanto así que los enfermos se lo solicitaban adjetivándolo como “droga milagrosa”. En este estudio se sostiene que esa consorte realizó una eficiente tarea en función de la distribución de las drogas a lo largo del país, con resultados tan positivos que, junto al resto de las actividades político sociales que impulsó, ayudó a la institucionalización de un nuevo rol de la esposa del Presidente.