| dc.creator | Gordón-Núñez,Manuel Antonio | |
| dc.creator | Godoy,Gustavo Pina | |
| dc.creator | Soares,Rosilene Calazans | |
| dc.creator | Souza,Lélia Batista de | |
| dc.creator | Freitas,Roseana de Almeida | |
| dc.creator | Queiroz,Lélia María Guedes | |
| dc.date | 2008-09-01 | |
| dc.date.accessioned | 2019-04-25T12:35:09Z | |
| dc.date.available | 2019-04-25T12:35:09Z | |
| dc.identifier | https://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0717-95022008000300010 | |
| dc.identifier.uri | http://revistaschilenas.uchile.cl/handle/2250/59729 | |
| dc.description | The aim of the study was to determine the immunohistochemical expression of the PCNA, p53 and bcl-2 proteins in pleomorphic adenomas.onineteen specimens of pleomorphic adenomas were selected for analysis by the streptavidin-biotin-peroxidase method with antibodies againstp53, PCNA and bcl-2 proteins. It was observedweak labeling for p53 in 12 cases (63.1%) andforPCNA in 8 (42.1%). With respect to the bcl-2 labeling index,ono expression of this protein was detected in 12 cases, corresponding to 63.1% of the sample. Based on these findings, it was concluded that p53 and PCNA can favor the proliferative activity of pleomorphic adenomas, whereas bcl-2 probably doesonot effectively particípate in the pathogenesis of this tumor. | |
| dc.format | text/html | |
| dc.language | en | |
| dc.publisher | Sociedad Chilena de Anatomía | |
| dc.relation | 10.4067/S0717-95022008000300010 | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.source | International Journal of Morphology v.26 n.3 2008 | |
| dc.subject | Pleomorphic adenoma | |
| dc.subject | Salivary gland tumour | |
| dc.subject | p53 | |
| dc.subject | PCNA | |
| dc.subject | bcl-2 | |
| dc.title | Inmunohistochemical Expression of PCNA, p53 and bcl-2 in Pleomorphic Adenomas | |
