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dc.creatorEnrione,Javier
dc.creatorOsorio,Fernando
dc.creatorLópez,Daniel
dc.creatorWeinstein-Oppenheimer,Caroline
dc.creatorFuentes,Miguel A
dc.creatorCeriani,Ricardo
dc.creatorBrown,Donald I
dc.creatorAlbornoz,Fernando
dc.creatorSánchez,Elizabeth
dc.creatorVillalobos,Patricio
dc.creatorSomoza,Rodrigo A
dc.creatorYoung,Manuel E
dc.creatorAcevedo,Cristian A
dc.date2010-09-01
dc.date.accessioned2019-05-03T12:44:46Z
dc.date.available2019-05-03T12:44:46Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0717-34582010000500020
dc.identifier.urihttp://revistaschilenas.uchile.cl/handle/2250/85161
dc.descriptionGelatin, chitosan and hyaluronic acid are natural components used to prepare polymeric scaffold in tissue engineering. The physical properties of these materials confer an appropriate microenvironment for cells, which can be used as a regeneration system for skin and cartilage. In this work, we prepared and characterized a Gelatin/Chitosan/Hyaluronan lyophilized-polymer. Physical properties of lyophilized-polymer changed slightly with moisture, but when polymer was totally hydrated the elasticity changed significantly. Thermophysical characterisation indicated that temperatures higher than 30ºC could modify irreversibly the polymeric matrix probably due to protein denaturation. Besides, we used the polymer as scaffold to prepare a biosynthetic-skin, reporting biological behaviour and its mechanical properties.
dc.formattext/html
dc.languageen
dc.publisherPontificia Universidad Católica de Valparaíso
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceElectronic Journal of Biotechnology v.13 n.5 2010
dc.subjectchitosan
dc.subjectfibrin
dc.subjectgelatin
dc.subjecthyaluronic acid
dc.subjectscaffold
dc.titleCharacterization of a Gelatin/Chitosan/Hyaluronan scaffold-polymer


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