The present study evaluates the effects of temperature (25 and 30°C) and salinity (25, 35 and 45 psu) on juvenile growth and survival. All the experiments were carried out under rearing conditions. A total of 270 specimens were used for the experiments. The results showed that more than 86% of the snapper survived at 35 to 45 psu salinity. Significant differences in growth parameters, such as the specific growth rate and weight gain were observed in fish reared at temperatures of 25 and 30°C and salinities of 35 and 45 psu. Increased salinity beyond 45 psu negatively affected growth of the Pacific red snapper used in this trial. The effects of temperature and salinity on growth performance a survival rate indicated that red snapper is an euryhaline species, that may tolerate wide salinity ranges, showing that has a good potential to grow in waters of lower salinity than the sea.