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dc.creatorCuchacovich T,Miguel
dc.creatorPacheco B,Patricio
dc.creatorMerino B,Guillermo
dc.creatorGallardo V,Patricia
dc.creatorGatica R,Héctor
dc.creatorValenzuela H,Hernán
dc.creatorVerdaguer D,Juan
dc.creatorVerdaguer T,Juan
dc.date2000-11-01
dc.date.accessioned2019-09-10T12:39:36Z
dc.date.available2019-09-10T12:39:36Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0034-98872000001100004
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/105315
dc.descriptionBackground: Scleritis and episcleritis may extend to adjacent ocular tissues with blinding consequences and may be associated with potentially lethal systemic disorders. Aim: To evaluate the ocular complications and systemic disease associations of the different types of scleritis and episcleritis. Patients and methods: Forty six patients with refractory scleritis and episcleritis were studied and treated during the period 1991 to 1998. Results: Necrotizing type was the most common and severe category in the scleritis group of patients. A decrease in vision occurred in 58.3% of patients with scleritis v/s a 23.5% of patients with epiescleritis (p<0,05). Uveitis was present in 35.4% of patients with scleritis and scleromalacia was present in 33.3% (p<0,05). A specific disease association was uncovered in 51% of scleritis and in 38% of episcleritis patients. Rheumatoid arthritis, primary systemic vasculitic disease and Sjögren syndrome with vasculitis were the most common associated systemic diseases. Three patients with scleritis had tuberculosis. Conclusions: Scleritis is more severe than episcleritis, and necrotizing scleritis is the most severe type of scleritis. Classification of scleritis and episcleritis provides valuable prognostic information. A meticulous approach for the detection of a specific associated disease must be undertaken. Scleritis associated with vasculitis has a worse ocular prognosis than other non infectious diseases. Cyclophosphamide is the most effective inmunosuppresive treatment to control severe ocular involvement (Rev Méd Chile 2000; 128: 1205-14)
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dc.publisherSociedad Médica de Santiago
dc.relation10.4067/S0034-98872000001100004
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceRevista médica de Chile v.128 n.11 2000
dc.subjectArthritis rheumatoid
dc.subjectEpiescleritis
dc.subjectScleral diseases
dc.subjectScleritis
dc.subjectSjögren syndrome
dc.subjectVasculitis
dc.titleCaracterísticas clínicas y respuesta al tratamiento sistémico de la epiescleritis y escleritis primarias y secundarias, refractarias al tratamiento local


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