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ACQUIRED APLASTIC ANEMIA. EXPERIENCE IN A PUBLIC HOSPITAL

Aplasia medular adquirida, experiencia en hospital público de referencia

dc.contributoren-US
dc.contributores-ES
dc.creatorLeón, Pilar; Universidad de Chile
dc.creatorCardemil, Daniela; Universidad de Chile
dc.creatorOsorio Paredes, Rocio; Universidad de Chile
dc.creatorPeña, Camila; Hospital del Salvador
dc.creatorValladares, Ximena; Hospital del Salvador
dc.creatorPuga, Bárbara; Hospital del Salvador
dc.creatorCabrera, María Elena; Universidad de Chile Hospital del Salvador
dc.date2018-01-19
dc.date.accessioned2019-11-11T18:27:11Z
dc.date.available2019-11-11T18:27:11Z
dc.identifierhttp://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/view/6072
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/111024
dc.descriptionBackground: The first line treatment for patients 70%. Aim: To report the experience with SCT and ATG for AA in a public hospital. Patients and methods: AA was diagnosed in 42 patients between 1998 and 2016, according to Camitta criteria. Thirty eight (90%) received treatment, 7 (18%) under 40 years old received SCT, and 31 (82%) IST. The rest were not treated. OS was calculated from date of diagnosis until last control, death or loss from follow up. Results: Complete or partial hematologic response, was obtained in 71% and 58% of cases with SCT and IS, respectively. Five year OS was 71% and 55% with SCT and IST, respectively. No difference in response was observed between horse and rabbit ATG. Conclusions: SCT from an HLA-identical sibling donor had a high response rate and survival. IST instead, had a lower response and survival, due to an initial high mortality rate.en-US
dc.descriptionBackground: The first line treatment for patients 70%. Aim: To report the experience with SCT and ATG for AA in a public hospital. Patients and methods: AA was diagnosed in 42 patients between 1998 and 2016, according to Camitta criteria. Thirty eight (90%) received treatment, 7 (18%) under 40 years old received SCT, and 31 (82%) IST. The rest were not treated. OS was calculated from date of diagnosis until last control, death or loss from follow up. Results: Complete or partial hematologic response, was obtained in 71% and 58% of cases with SCT and IS, respectively. Five year OS was 71% and 55% with SCT and IST, respectively. No difference in response was observed between horse and rabbit ATG. Conclusions: SCT from an HLA-identical sibling donor had a high response rate and survival. IST instead, had a lower response and survival, due to an initial high mortality rate.es-ES
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dc.languagespa
dc.publisherRevista Médica de Chilees-ES
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dc.sourceRevista Médica de Chile; Vol. 146, núm. 2 (2018): FEBRERO 2018es-ES
dc.source0034-9887
dc.subjectAnemia; Aplastic; Homologous; Immunosuppression; Stem Cell Transplantation; Transplatationen-US
dc.subjectAnemia; Aplastic; Homologous; Immunosuppression; Stem Cell Transplantation; Transplantationes-ES
dc.titleACQUIRED APLASTIC ANEMIA. EXPERIENCE IN A PUBLIC HOSPITALen-US
dc.titleAplasia medular adquirida, experiencia en hospital público de referenciaes-ES
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typees-ES


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