| dc.creator | Benites, Julio | |
| dc.creator | Guerrero Castilla, Angélica | |
| dc.creator | Salas, Felipe | |
| dc.creator | Martinez, José L. | |
| dc.creator | Jara Aguilar, Rafael | |
| dc.creator | Venegas Casanova, Edmundo A. | |
| dc.creator | Suarez Rebaza, Luz | |
| dc.creator | Guerrero Hurtado, Juana | |
| dc.creator | Buc Calderón, Pedro | |
| dc.date | 2018-12-02 | |
| dc.date.accessioned | 2019-04-15T14:50:34Z | |
| dc.date.available | 2019-04-15T14:50:34Z | |
| dc.identifier | http://www.revistas.usach.cl/ojs/index.php/blacpma/article/view/3519 | |
| dc.identifier.uri | http://revistaschilenas.uchile.cl/handle/2250/34890 | |
| dc.description | The composition of the essential oil obtained by hydrodistillation from Minthostachys mollis Griseb (Lamiaceae) aerial parts was determined by GC and GC/MS. Menthone (13.2%), pulegone (12.4%), cis-dihydrocarvone (9.8%) and carvacrol acetate (8.8%) were the main essential oil components. The cytotoxic activity of the essential oil was in vitro measured using the MTT colorimetric assay. IC50values were calculated on healthy non-tumor cells (HEK-293) and three human cancer cell lines (T24, DU-145 and MCF-7). In such latter cells, the estimated values were around 0.2 mg/mL. In addition, the antioxidant activity was determined by interaction with the stable freeradical 2,2”-diphenyl-1-picrylhydrazyl. The essential oil was almost devoid of antioxidant activity indicating that its anti-proliferative action relies on other unknown mechanism. | es-ES |
| dc.format | application/pdf | |
| dc.language | spa | |
| dc.publisher | Universidad de Santiago de Chile | es-ES |
| dc.relation | http://www.revistas.usach.cl/ojs/index.php/blacpma/article/view/3519/26002834 | |
| dc.source | Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas; Vol. 17 Núm. 6 (2018): Vol 17, No 6: BLACPMA, Noviembre 2018; 566 - 574 | es-ES |
| dc.source | 0717-7917 | |
| dc.title | Chemical composition, in vitro cytotoxic and antioxidant activities of the essential oil of Peruvian Minthostachys mollis Griseb | es-ES |
| dc.type | info:eu-repo/semantics/article | |
| dc.type | info:eu-repo/semantics/publishedVersion | |
