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dc.creatorBenites, Julio
dc.creatorGuerrero Castilla, Angélica
dc.creatorSalas, Felipe
dc.creatorMartinez, José L.
dc.creatorJara Aguilar, Rafael
dc.creatorVenegas Casanova, Edmundo A.
dc.creatorSuarez Rebaza, Luz
dc.creatorGuerrero Hurtado, Juana
dc.creatorBuc Calderón, Pedro
dc.date2018-12-02
dc.date.accessioned2019-04-15T14:50:34Z
dc.date.available2019-04-15T14:50:34Z
dc.identifierhttp://www.revistas.usach.cl/ojs/index.php/blacpma/article/view/3519
dc.identifier.urihttp://revistaschilenas.uchile.cl/handle/2250/34890
dc.descriptionThe composition of the essential oil obtained by hydrodistillation from Minthostachys mollis Griseb (Lamiaceae) aerial parts was determined by GC and GC/MS. Menthone (13.2%), pulegone (12.4%), cis-dihydrocarvone (9.8%) and carvacrol acetate (8.8%) were the main essential oil components. The cytotoxic activity of the essential oil was in vitro measured using the MTT colorimetric assay. IC50values were calculated on healthy non-tumor cells (HEK-293) and three human cancer cell lines (T24, DU-145 and MCF-7). In such latter cells, the estimated values were around 0.2 mg/mL. In addition, the antioxidant activity was determined by interaction with the stable freeradical 2,2”-diphenyl-1-picrylhydrazyl. The essential oil was almost devoid of antioxidant activity indicating that its anti-proliferative action relies on other unknown mechanism.es-ES
dc.formatapplication/pdf
dc.languagespa
dc.publisherUniversidad de Santiago de Chilees-ES
dc.relationhttp://www.revistas.usach.cl/ojs/index.php/blacpma/article/view/3519/26002834
dc.sourceBoletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas; Vol. 17 Núm. 6 (2018): Vol 17, No 6: BLACPMA, Noviembre 2018; 566 - 574es-ES
dc.source0717-7917
dc.titleChemical composition, in vitro cytotoxic and antioxidant activities of the essential oil of Peruvian Minthostachys mollis Grisebes-ES
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion


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