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dc.creatorURQUIAGA,INÉS
dc.creatorGUASCH,VIVIANA
dc.creatorMARSHALL,GUILLERMO
dc.creatorSAN MARTÍN,ALEJANDRA
dc.creatorCASTILLO,ÓSCAR
dc.creatorROZOWSKI,JAIME
dc.creatorLEIGHTON,FEDERICO
dc.date2004-01-01
dc.date.accessioned2019-05-02T21:21:16Z
dc.date.available2019-05-02T21:21:16Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0716-97602004000200012
dc.identifier.urihttp://revistaschilenas.uchile.cl/handle/2250/81512
dc.descriptionThe type of diet consumed by individuals has been associated with the development of some chronic diseases, including cardiovascular disease (CVD), cancer, diabetes, and others. Populations that consume diets rich in fruits and vegetables and drink wine in moderation, as the Mediterranean, have a higher life expectancy and less chronic diseases than other occidental populations. We carried out an intervention study in humans to evaluate the effect of a Mediterranean diet (MD), an Occidental diet (OD) and their supplementation with red wine, on biochemical, physiological and clinical parameters related to atherosclerosis and other chronic diseases. For 3 months, two groups of 21 male volunteers each, received either a MD or an OD; during the second month, red wine was added isocalorically, 240 ml/day. At days 0, 30, 60 and 90, clinical, physiological and biochemical evaluations were made. In this article we report on the results obtained in plasma fatty acids profile that includes saturated fatty acids (SFA), monounsaturated fatty acids (MUFA), polyunsaturated fatty acids (PUFA), w-6 fatty acids, w-3 fatty acids and w-6/w-3 ratio. Other results have been published previously. Plasma fatty acid percentages in the OD group, compared to the MD group, did not show differences in SFA, but the OD group showed lower levels of MUFA and w-3 fatty acids, and higher levels of PUFA and w-6 fatty acids, with a higher w-6/w-3 ratio than the MD group. Wine supplementation reduced MUFA and increased PUFA in both dietary groups, suggesting that wine could improve a diet with a good w-6/w-3 ratio. Volunteers on MD showed a better fatty acid profile than those on OD, suggesting a lower cardiovascular risk. Moderate consumption of wine improves this profile in the MD group.
dc.formattext/html
dc.languageen
dc.publisherSociedad de Biología de Chile
dc.relation10.4067/S0716-97602004000200012
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceBiological Research v.37 n.2 2004
dc.subjectCardiovascular disease
dc.subjectchronic diseases
dc.subjectfatty acids
dc.subjectMediterranean diet
dc.subjectmonounsaturated fatty acids (MUFA)
dc.subjectOccidental diet
dc.subjectw-6 fatty acids
dc.subjectw-3 fatty acids
dc.subjectplasma fatty acids
dc.subjectpolyunsaturated fatty acids (PUFA)
dc.subjectsaturated fatty acids (SFA)
dc.subjectwine
dc.titleEffect of Mediterranean and Occidental Diets, and Red Wine, on Plasma Fatty Acids in Humans: An Intervention Study


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